See all properties

21c Museum Hotel Louisville

4.5 star property
4.5-star luxury hotel near KFC Yum Center

Choose dates to view prices

Photo gallery for 21c Museum Hotel Louisville

Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
Interior
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
Breakfast, lunch and dinner served
Fountain

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Spa
  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Gym

Explore the area

View in a map
700 W Main Street, Louisville, KY, 40202
  • Place, 21c Museum Hotel
    ‪1 min walk‬
  • Place, Louisville Slugger Museum
    ‪3 min walk‬
  • Place, KFC Yum Center
    ‪8 min walk‬
  • Airport, Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

Room options

View all photos for Deluxe Double Room, 2 Double Beds

Deluxe Double Room, 2 Double Beds | Premium bedding, down comforters, minibar, in-room safe

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(31 reviews)
  • 335 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds | Premium bedding, down comforters, minibar, in-room safe

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 435 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(68 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(34 reviews)
  • City view
  • 455 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner | Premium bedding, down comforters, minibar, in-room safe

Suite, Corner

  • City view
  • 660 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

Room (Asleep in the Cyclone)

  • 500 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Suite (Atrium)

Suite (Atrium) | Premium bedding, down comforters, minibar, in-room safe

Suite (Atrium)

  • 580 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room, Balcony

Room, Balcony | Premium bedding, down comforters, minibar, in-room safe

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • City view
  • 315 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Double Room, Accessible

Designer toiletries, hair dryer, bathrobes, towels

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 455 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 434 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 435 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop) | Premium bedding, down comforters, minibar, in-room safe

Apartment, 1 Double Bed (Rooftop)

  • City view
  • Sleeps 4
  • 1 Double Bed

You may also like

Ad
Restaurant

Aloft Louisville Downtown

Downtown Louisville
  • Pet friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.5 out of 5, Wonderful, 1,002 reviews
$112 nightly
The price is $131
Mar 15 - Mar 16
Total with taxes and fees
Aloft Louisville Downtown

About the neighborhood

Louisville

Downtown Louisville stay.A stay at this Downtown Louisville hotel places you steps from Louisville Slugger Museum and within a 10-minute walk of KFC Yum Center. Ohio River Valley and 21c Museum Hotel are also within half a mile (1 km).

What's nearby

  • 21c Museum Hotel - 1 min walk - 0.0 miles
  • Louisville Slugger Museum - 3 min walk - 0.2 miles
  • Kentucky International Convention Center - 8 min walk - 0.5 miles
  • KFC Yum Center - 8 min walk - 0.5 miles
  • Whiskey Row - 8 min walk - 0.5 miles

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪Jockey Silks Bourbon Bar - ‬7 min walk
  • ‪Heine Brothers' Coffee - ‬3 min walk
  • ‪Vincenzo's Italian Restaurant - ‬5 min walk
  • ‪Swizzle - ‬8 min walk
  • ‪Sunergos Coffee and Espresso Bar - ‬6 min walk

About this property

21c Museum Hotel Louisville

4.5-star luxury hotel near KFC Yum Center
21c Museum Hotel Louisville offers its guests a full-service spa and a 24-hour fitness center. There's a restaurant on site. You can enjoy a drink at the bar/lounge. A computer station is on site, and both WiFi and wired Internet are free in public spaces.

A 24-hour business center, meeting rooms, and limo/town car service are available. Event space at this hotel measures 5000 square feet (465 square meters) and includes conference space. Spa services, multilingual staff, and gift shops/newsstands are also featured at the luxury 21c Museum Hotel Louisville. Parking is available for a fee.

This 4.5-star Louisville hotel is smoke free.

  • 1 building
  • 91 guestrooms or units
  • 4 levels
  • Meeting rooms
  • 5000 sq ft of conference space
  • 465 sq m of conference space
  • Built in 2006
  • Charging station for electric cars
  • Business center (24 hours)
  • Conference space
  • Breakfast available (surcharge)
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Staff is multilingual
  • Storage area for luggage
  • Front-desk safe
  • Car service
  • Tour and ticket information
  • Concierge
  • Gift shop
  • ATM
  • Bellhop
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Dining venue
21c Museum Hotel Louisville offers 91 accommodations with minibars and laptop-compatible safes. Beds feature down comforters and premium bedding. 50-inch LCD televisions come with premium cable channels. Bathrooms include bathrobes, designer toiletries, complimentary toiletries, and hair dryers.

This Louisville hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Additionally, rooms include espresso makers and complimentary bottled water. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided daily.

21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages, and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.

Similar properties

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham
  • Pool
  • Spa
  • Pet friendly
  • Free WiFi
4.5 out of 5, Wonderful, 4,068 reviews
$160 nightly
The price is $188
Feb 16 - Feb 17
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham

Property amenities

Family friendly

  • In-room crib
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Wheelchair-accessible parking available

Food and drink

  • Full breakfast available for a fee 7:00 AM to 10:00 AM on weekdays and 8:00 AM to 1:00 PM on weekends; USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

Room amenities

Entertainment

  • 50-inch LCD TV with premium cable channels
  • iPod dock

Bedroom

  • Blackout drapes
  • Down comforter
  • Free crib
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathrobes
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Champagne service
  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 40.00 per accommodation, per stay
  • Weight limit: 50 lbs per pet
  • Food and water bowls are available
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are available for USD 30.0 per night.
  • Free cribs (infant beds)!

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5.00 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
Charges for extra guests may apply and vary according to property policy.
A credit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, and Discover. Cash is not accepted. This property uses eco-friendly cleaning products.
    For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards in each accommodation. This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels).

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
21c Museum Hotel Louisville - MGallery Louisville
Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
21c Museum Louisville Mgallery
21c Museum Louisville
21c Museum Hotel Louisville Hotel
21c Museum Hotel Louisville MGallery
21c Museum Hotel Louisville Louisville
21c Museum Hotel Louisville Hotel Louisville

Frequently asked questions

How close is 21c Museum Hotel Louisville to the airport?

21c Museum Hotel Louisville is 7.1 mi (10-min drive) away from the Louisville Intl. Airport (SDF) airport, the closest popular airport to the property.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of Feb 14, 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on Feb 17, 2026 start from $179.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does 21c Museum Hotel Louisville have an airport shuttle?

Airport shuttle services are not available at 21c Museum Hotel Louisville.

Does 21c Museum Hotel Louisville offer free breakfast?

Free breakfast isn’t provided at 21c Museum Hotel Louisville, but full breakfast is offered for a fee of between USD 5 and 25 per person. It's available on weekdays from 7:00 AM to 10:00 AM and weekends from 8:00 AM to 1:00 PM.

Is there a casino at 21c Museum Hotel Louisville?

No, there is no casino at this hotel, but Horseshoe Southern Indiana Casino (22-min drive) is nearby.

What time is check-in at 21c Museum Hotel Louisville?

Check-in start time: 4 PM; Check-in end time: midnight.

Is there free parking at 21c Museum Hotel Louisville?

Free parking is not available at this hotel. Valet parking is available for USD 32 per night.

Does 21c Museum Hotel Louisville have a pool?

21c Museum Hotel Louisville does not have a pool.

Does 21c Museum Hotel Louisville have a restaurant?

21c Museum Hotel Louisville is home to Proof on Main, which features light fare and brunch.

Does 21c Museum Hotel Louisville have a spa?

Pamper yourself with a day at 21c Spa, where you can enjoy hot stone massages.

How close is 21c Museum Hotel Louisville to downtown Louisville?

21c Museum Hotel Louisville is 0.4 mi away from Louisville.

21c Museum Hotel Louisville Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 769 out of 1004 reviews
Rating 8 - Good. 133 out of 1004 reviews
Rating 6 - Okay. 62 out of 1004 reviews
Rating 4 - Poor. 22 out of 1004 reviews
Rating 2 - Terrible. 18 out of 1004 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Jan Elliott

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent in every way. The art museum was an added bonus!!!
Stayed 3 nights in Nov 2025

10/10 Excellent

Glenn

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Room comfortable and clean. Staff very helpful and friendly. Loved the art!
Stayed 1 night in Nov 2025

10/10 Excellent

david

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Beautiful environment Helpful friendly staff
Stayed 1 night in Nov 2025

8/10 Good

ABBEY

Traveled with family
Liked: Cleanliness
Bed was comfortable, room was large, bathroom was OK. Staff was kind. Wish the breakfast opened earlier on Sunday.
Stayed 3 nights in Oct 2025

10/10 Excellent

Matthew

Stayed 2 nights in Oct 2025

10/10 Excellent

John

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Oct 2025

10/10 Excellent

Robin, Safety Harbor

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21c Museum Hotel is a fun and unique experience. Beautiful rooms and centrally located to shops, restaurants and distilleries in Louisville.
Stayed 2 nights in Oct 2025

8/10 Good

Richard

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast had a good variety but in some cases a little over cooked. Right on whiskey row, plenty of dining options
Stayed 3 nights in Oct 2025

10/10 Excellent

Steven

Stayed 2 nights in Oct 2025

10/10 Excellent

Erica

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved our stay, would definitely plan to come back if we are ever in the area again.
Stayed 1 night in Oct 2025

10/10 Excellent

Melissa

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We've wanted to stay at a 21c Museum hotel. We love the concept. And the room was large and well appointed. Staff was A+. We highly recommend when visiting Louisville.
Stayed 1 night in Oct 2025

8/10 Good

Thomas

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Front desk and valets were great. But our room wasn't serviced, which makes the stay less comfortable.
Stayed 2 nights in Oct 2025

10/10 Excellent

Savannah

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Natalie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Oct 2025

10/10 Excellent

Stephanie

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the strange art. I thought the building maintained the character I was expecting by the name and the reviews. Gym was actually better than the reviews.
Stayed 2 nights in Oct 2025

10/10 Excellent

earl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location for walking Louisville
Stayed 4 nights in Oct 2025

8/10 Good

Pamela

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Nice art
Stayed 1 night in Oct 2025

6/10 Okay

Kevin

Stayed 3 nights in Oct 2025

10/10 Excellent

Shelley

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We only stayed 1 night, but everything was excellent
Stayed 1 night in Oct 2025

10/10 Excellent

Courtney

Liked: Cleanliness
Stayed 1 night in Sep 2025

8/10 Good

mirtha

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location
Stayed 2 nights in Oct 2025

10/10 Excellent

Ralph

Stayed 1 night in Sep 2025

8/10 Good

mark

Traveled with partner, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Price was too high compared to similar hotels.
Stayed 2 nights in Sep 2025

2/10 Terrible

Uzeir

Stayed 1 night in Sep 2025

10/10 Excellent

Jeannette

Liked: Cleanliness, staff & service, property conditions & facilities
Great stay overall.
Stayed 2 nights in Sep 2025