Vuelos de American Airlines de Knoxville (TYS) a San Francisco (SFO) desde $143

Ensure you go to our Covid-19 Travel Advisor to learn if there are any current quarantine requirements or travel advice reports in place in SFO when flying from McGhee Tyson Airport (TYS).

As soon as you get your ticket for your American Airlines flight from McGhee Tyson Airport (TYS) to San Francisco Airport, check if the terminal details are on it. If not, you might like to get in touch with your air carrier. They’ll be able to tell you where you’ll be flying into and out of.

American Airlines doesn’t provide direct flights between Knoxville Airport and San Francisco Airport, so be prepared to make a stopover. If you’re not pushed for time between flights, hit the airport shops while waiting for your connection.

Depending on no delays and good weather, your American Airlines flight from Knoxville Airport to SFO should take about 6 hours and 58 minutes. You’ll have plenty of time to enjoy a meal, catch forty winks and revise your travel schedule before you land.

If you’re thinking about a journey from TYS to SFO, you can pick from about 4 American Airlines flights per day.

For more info about changing your flight to San Francisco Airport, please visit our Customer Service Portal.

This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.

Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.

Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.