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Top Mission Bay Spa Hotels

See all 302 Hotels in Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

3999 Mission Boulevard, San Diego
4.5 out of 5.0
4.3 out of 5 (230 reviews)

Facing the calm expanse of Mission Bay in north San Diego, and a 3-minute walk from the sands and famous boardwalk of Pacific Beach, family-friendly Catamaran ...

Honeymoon GetawayHotel staff was excellent! Super friendly and always willing to help. From the front desk to restaurant staff, even housekeeping & grounds staff always greeted us warmly and went out of their way to make us feel welcome. Booked here for our honeymoon due to location and we were not disappointed. ...
  Dec 18, 2017

$179

$179
Hilton San Diego Resort & Spa

Hilton San Diego Resort & Spa

1775 E Mission Bay Dr, San Diego
4.5 out of 5.0
3.5 out of 5 (52 reviews)

Hilton San Diego Resort & Spa is set among tropical gardens and close to sandy beaches on the shores of Mission Bay. This 18-acre resort is just 2 mi (3 km) ...

Relaxing, quiet placeVery reasonable prices. We had a ground floor room which was a little smelly. When we mentioned it to staff they immediately upgraded our room. We were very pleased with the 6 floor room. This hotel is off the main drag and super quiet and relaxing!
  Dec 7, 2017

$152

$152
Paradise Point Resort & Spa

Paradise Point Resort & Spa

1404 Vacation Rd, San Diego
4.0 out of 5.0
3.9 out of 5 (173 reviews)

Paradise Point Resort & Spa is on a private tropical island in San Diego’s Mission Bay. SeaWorld® is a 4-minute drive away over Mission Bay’s South Cove, and ...

Good but serious problemsOverall a good place for a relaxing stay. However I had two problems - We had our room fully paid for but, the card for incidentals had a problem on our last night and they LOCKED us out of the room .... after a long day out with kids and dinner in hand! They would not let us into our PAID IN FULL ...
  Dec 31, 2017

$139

$139
Bahia Resort Hotel

Bahia Resort Hotel

998 W Mission Bay Dr, San Diego
3.5 out of 5.0
3.8 out of 5 (152 reviews)

Only 8 miles from the airport, Bahia Resort Hotel is secluded on a 14-acre peninsula along the shores of Mission Bay, just 1 block from Mission Beach and a short ...

Great family fun Great place for family Nice free arcade games. Kevin was great at check in
  Aug 19, 2017

$159

$159
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd, San Diego
4.5 out of 5.0
4.0 out of 5 (108 reviews)

Located on the shores of San Diego's Mission Bay, the Hyatt Regency Mission Bay Spa and Marina is a quarter-mile from SeaWorld and Mission Beach, and 3 miles ...

Pleasant StayWe stayed here for 4 nights and overall it was a good experience. Staff was very nice and helpful. I loved all of the activities that were included in the stay.
  Dec 11, 2017

$119

$119
The Dana on Mission Bay

The Dana on Mission Bay

1710 W Mission Bay Dr, San Diego
4.0 out of 5.0
3.9 out of 5 (205 reviews)

Adjacent to San Diego's Mission Bay, this 13-acre hotel is within 2 miles of SeaWorld and Mission Beach, and 6 miles of the San Diego Zoo.

Nice hotel in a great location!!Had a very good time and would definitely stay again.
  Feb 6, 2018

$97

$97
La Quinta Inn & Suites San Diego Mission Bay

La Quinta Inn & Suites San Diego Mission Bay

4610 De Soto St, San Diego
3.5 out of 5.0
3.8 out of 5 (57 reviews)

Located in Pacific Beach, this hotel is within 6 mi (10 km) of Mission Bay Park, University of San Diego, and La Jolla Cove. SeaWorld and University of California-San ...

Great staffStaff and hotel room was great. Parking spaces on second level were not big enough for our small car (Toyota Corolla), had a hard time finding a space where either the cars on either side of us or we could get in or out of the car. Very tight. Room and staff were wonderful, we didn't check out the ...
  Dec 14, 2016

$80

$80
2BR Remodeled Home Pool and Hot Tub by RedAwning

2BR Remodeled Home Pool and Hot Tub by RedAwning

1655 La Playa Ave, San Diego
4.0 out of 5.0

Located in Pacific Beach, this vacation home is 1.2 mi (1.9 km) from Mission Bay Park and within 3 mi (5 km) of SeaWorld and Mission Beach. Mission Bay Golf ...

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Travelers Like You Recently Booked These Mission Bay Hotels

Bahia Resort Hotel
3.5 out of 5.0
Last booking: 7 minutes ago
La Quinta Inn & Suites San Diego Mission Bay
3.5 out of 5.0
Last booking: 14 minutes ago
Red Roof Inn San Diego - Pacific Beach/SeaWorld Area
2.0 out of 5.0
Last booking: 1 hour ago
Hyatt Regency Mission Bay Spa and Marina
4.5 out of 5.0
Last booking: 2 hours ago
Hilton San Diego Resort & Spa
4.5 out of 5.0
Last booking: 2 hours ago
Catamaran Resort and Spa
4.5 out of 5.0
Last booking: 2 hours ago
Paradise Point Resort & Spa
4.0 out of 5.0
Last booking: 2 hours ago
The Dana on Mission Bay
4.0 out of 5.0
Last booking: 3 hours ago
Holiday Inn Express San Diego Sea World - Beach Area
3.0 out of 5.0
Last booking: 7 hours ago

There is nothing more refreshing than a day at the spa. And the pure relaxation of spa hotels in Mission Bay is the epitome of rejuvenation. Pamper yourself while in Mission Bay with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Mission Bay offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Mission Bay spa hotels, and prepare to relax.