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Featured Panama City 5 Star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Panama City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Panama City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Panama City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Panama City hotels essential information

Accommodation
945 hotels
Lowest Price
$106
Highest Price
$276
Popular hotels
Hotel Riu Plaza Panama, Waldorf Astoria Panama, W Panama, JW Marriott Panama, Sofitel Legend Casco Viejo, Panama City , Hilton Panama, The Westin Playa Bonita Panama, The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City, Bristol Panama, a Registry Collection Hotel, Villa Palma Boutique Hotel

Recent Panama City hotel reviews by fellow wanderers